7y5t

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7y5t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y5T FirstGlance]. <br>
<table><tr><td colspan='2'>[[7y5t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y5T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=IGD:~{N}-[4-[2,5-bis(fluoranyl)phenyl]-4-(4-chlorophenyl)sulfonyl-cyclohexyl]-1,1,1-tris(fluoranyl)methanesulfonamide'>IGD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=IGD:~{N}-[4-[2,5-bis(fluoranyl)phenyl]-4-(4-chlorophenyl)sulfonyl-cyclohexyl]-1,1,1-tris(fluoranyl)methanesulfonamide'>IGD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y5t OCA], [https://pdbe.org/7y5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y5t RCSB], [https://www.ebi.ac.uk/pdbsum/7y5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y5t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y5t OCA], [https://pdbe.org/7y5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y5t RCSB], [https://www.ebi.ac.uk/pdbsum/7y5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y5t ProSAT]</span></td></tr>
</table>
</table>
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</div>
</div>
<div class="pdbe-citations 7y5t" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7y5t" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Gamma secretase|Gamma secretase]]
== References ==
== References ==
<references/>
<references/>

Current revision

CryoEM structure of PS1-containing gamma-secretase in complex with MRK-560

PDB ID 7y5t

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