8ua3

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Current revision (08:08, 6 November 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8ua3 is ON HOLD until Paper Publication
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==Cryo-EM Structure of FBOX22-BACH1BTB==
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<StructureSection load='8ua3' size='340' side='right'caption='[[8ua3]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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Authors: Shi, H., Cao, S., Zheng, N.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ua3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UA3 FirstGlance]. <br>
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Description: Cryo-EM Structure of FBOX22-BACH1BTB
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ua3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ua3 OCA], [https://pdbe.org/8ua3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ua3 RCSB], [https://www.ebi.ac.uk/pdbsum/8ua3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ua3 ProSAT]</span></td></tr>
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[[Category: Shi, H]]
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</table>
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[[Category: Cao, S]]
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== Function ==
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[[Category: Zheng, N]]
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[https://www.uniprot.org/uniprot/FBX22_HUMAN FBX22_HUMAN] Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.<ref>PMID:22972877</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cao S]]
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[[Category: Shi H]]
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[[Category: Zheng N]]

Current revision

Cryo-EM Structure of FBOX22-BACH1BTB

PDB ID 8ua3

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