2qo3

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Current revision (09:27, 6 November 2024) (edit) (undo)
 
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<StructureSection load='2qo3' size='340' side='right'caption='[[2qo3]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='2qo3' size='340' side='right'caption='[[2qo3]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qo3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_erythreus"_(sic)_waksman_1923 "actinomyces erythreus" (sic) waksman 1923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QO3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qo3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QO3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CER:(2S,+3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE'>CER</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hg4|2hg4]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CER:(2S,+3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE'>CER</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eryAII ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1836 "Actinomyces erythreus" (sic) Waksman 1923])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/6-deoxyerythronolide-B_synthase 6-deoxyerythronolide-B synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.94 2.3.1.94] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qo3 OCA], [https://pdbe.org/2qo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qo3 RCSB], [https://www.ebi.ac.uk/pdbsum/2qo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qo3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qo3 OCA], [https://pdbe.org/2qo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qo3 RCSB], [https://www.ebi.ac.uk/pdbsum/2qo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qo3 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ERYA2_SACER ERYA2_SACER]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qo/2qo3_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qo/2qo3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6-deoxyerythronolide-B synthase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cane, E D]]
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[[Category: Saccharopolyspora erythraea]]
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[[Category: Chen, Y A]]
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[[Category: Cane ED]]
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[[Category: Khosla, C]]
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[[Category: Chen YA]]
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[[Category: Kim, C Y]]
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[[Category: Khosla C]]
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[[Category: Tang, Y]]
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[[Category: Kim CY]]
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[[Category: Acyltransferase]]
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[[Category: Tang Y]]
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[[Category: Ketosynthase]]
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[[Category: Phosphopantetheine]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase

PDB ID 2qo3

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