2vax

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Current revision (09:31, 6 November 2024) (edit) (undo)
 
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<StructureSection load='2vax' size='340' side='right'caption='[[2vax]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2vax' size='340' side='right'caption='[[2vax]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vax]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Acrch Acrch]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VAX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vax]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Acremonium_chrysogenum Acremonium chrysogenum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VAX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSC:4-(3-ACETOXYMETHYL-2-CARBOXY-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-EN-7-YLCARBAMOYL)-1-CARBOXY-BUTYL-AMMONIUM'>CSC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSC:4-(3-ACETOXYMETHYL-2-CARBOXY-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-EN-7-YLCARBAMOYL)-1-CARBOXY-BUTYL-AMMONIUM'>CSC</scene>, <scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vat|2vat]], [[2vav|2vav]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Deacetylcephalosporin-C_acetyltransferase Deacetylcephalosporin-C acetyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.175 2.3.1.175] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vax OCA], [https://pdbe.org/2vax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vax RCSB], [https://www.ebi.ac.uk/pdbsum/2vax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vax ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vax OCA], [https://pdbe.org/2vax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vax RCSB], [https://www.ebi.ac.uk/pdbsum/2vax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vax ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CEFG_ACRCH CEFG_ACRCH]] Catalyzes the conversion of deacetylcephalosporin C to cephalosporin C.
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[https://www.uniprot.org/uniprot/CEFG_HAPCH CEFG_HAPCH] Catalyzes the conversion of deacetylcephalosporin C to cephalosporin C.<ref>PMID:1569032</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vax_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vax_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acrch]]
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[[Category: Acremonium chrysogenum]]
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[[Category: Deacetylcephalosporin-C acetyltransferase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ellis, J]]
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[[Category: Ellis J]]
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[[Category: Lejon, S]]
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[[Category: Lejon S]]
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[[Category: Valegard, K]]
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[[Category: Valegard K]]
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[[Category: A/b-hydrolase fold]]
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[[Category: Acetyl transferase]]
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[[Category: Acyltransferase]]
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[[Category: Antibiotic biosynthesis]]
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[[Category: Cephalosporin biosynthesis]]
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[[Category: Deacetylcephalosporin c]]
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[[Category: Transferase]]
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Current revision

Crystal structure of deacetylcephalosporin C acetyltransferase (Cephalosporin C-soak)

PDB ID 2vax

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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