4jjh
From Proteopedia
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== Disease == | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/NECT4_HUMAN NECT4_HUMAN] Ectodermal dysplasia-syndactyly syndrome. The disease is caused by variants affecting the gene represented in this entry. | + | [https://www.uniprot.org/uniprot/NECT4_HUMAN NECT4_HUMAN] Ectodermal dysplasia-pili torti-cutaneous syndactyly syndrome. The disease is caused by variants affecting the gene represented in this entry. |
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NECT4_HUMAN NECT4_HUMAN] Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.<ref>PMID:22048310</ref> <ref>PMID:23202587</ref> | [https://www.uniprot.org/uniprot/NECT4_HUMAN NECT4_HUMAN] Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.<ref>PMID:22048310</ref> <ref>PMID:23202587</ref> | ||
Current revision
Crystal structure of the D1 domain from human Nectin-4 extracellular fragment [PSI-NYSGRC-005624]
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Categories: Homo sapiens | Large Structures | Ahmed M | Almo SC | Banu R | Bhosle R | Bonanno J | Calarese D | Celikigil A | Chamala S | Chan MK | Chowdhury S | Fiser A | Garforth S | Glenn AS | Hillerich B | Khafizov K | Kumar PR | Love J | Nathenson SG | Patel H | Seidel R | Stead M | Toro R
