5sdc
From Proteopedia
(Difference between revisions)
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<StructureSection load='5sdc' size='340' side='right'caption='[[5sdc]], [[Resolution|resolution]] 1.93Å' scene=''> | <StructureSection load='5sdc' size='340' side='right'caption='[[5sdc]], [[Resolution|resolution]] 1.93Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SDC FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.928Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.928Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LDV:3-[(4-methylpiperidin-1-yl)methyl]-1H-indole'>LDV</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LDV:3-[(4-methylpiperidin-1-yl)methyl]-1H-indole'>LDV</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sdc OCA], [https://pdbe.org/5sdc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sdc RCSB], [https://www.ebi.ac.uk/pdbsum/5sdc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sdc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sdc OCA], [https://pdbe.org/5sdc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sdc RCSB], [https://www.ebi.ac.uk/pdbsum/5sdc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sdc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/DPP11_PORG3 DPP11_PORG3] Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA. Is involved in amino acid metabolism and bacterial growth of asaccharolytic P.gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.<ref>PMID:21896480</ref> <ref>PMID:23246913</ref> | ||
==See Also== | ==See Also== | ||
*[[Dipeptidyl peptidase 3D structures|Dipeptidyl peptidase 3D structures]] | *[[Dipeptidyl peptidase 3D structures|Dipeptidyl peptidase 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Porphyromonas gingivalis]] | ||
[[Category: Bezerra GA]] | [[Category: Bezerra GA]] | ||
[[Category: Bountra C]] | [[Category: Bountra C]] | ||
Current revision
PanDDA analysis group deposition -- Crystal Structure of Porphyromonas gingivalis in complex with Z2856434912
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Categories: Large Structures | Bezerra GA | Bountra C | Coker JA | Douangamath A | Fearon D | Foster WR | Koekemoer L | Krojer T | Talon R | Tham CT | Yue WW | Von Delft F
