6fax
From Proteopedia
(Difference between revisions)
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==Complex of Human CD40 Ectodomain with Lob 7.4 Fab== | ==Complex of Human CD40 Ectodomain with Lob 7.4 Fab== | ||
- | <StructureSection load='6fax' size='340' side='right' caption='[[6fax]], [[Resolution|resolution]] 2.99Å' scene=''> | + | <StructureSection load='6fax' size='340' side='right'caption='[[6fax]], [[Resolution|resolution]] 2.99Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6fax]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6fax]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FAX FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99Å</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fax OCA], [https://pdbe.org/6fax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fax RCSB], [https://www.ebi.ac.uk/pdbsum/6fax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fax ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
- | [ | + | [https://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN] Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) [MIM:[https://omim.org/entry/606843 606843]. A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.<ref>PMID:11675497</ref> |
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN] Receptor for TNFSF5/CD40LG. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6fax" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6fax" style="background-color:#fffaf0;"></div> | ||
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+ | ==See Also== | ||
+ | *[[Antibody 3D structures|Antibody 3D structures]] | ||
+ | *[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Orr CM]] |
- | [[Category: | + | [[Category: Pearson AR]] |
- | [[Category: | + | [[Category: Tews I]] |
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Current revision
Complex of Human CD40 Ectodomain with Lob 7.4 Fab
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