1u75

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[[Image:1u75.jpg|left|200px]]
[[Image:1u75.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1u75 |SIZE=350|CAPTION= <scene name='initialview01'>1u75</scene>, resolution 2.55&Aring;
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The line below this paragraph, containing "STRUCTURE_1u75", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZNH:PROTOPORPHYRIN+IX+CONTAINING+ZN'>ZNH</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= Yeast ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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-->
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|DOMAIN=
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{{STRUCTURE_1u75| PDB=1u75 | SCENE= }}
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|RELATEDENTRY=[[1u74|1U74]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u75 OCA], [http://www.ebi.ac.uk/pdbsum/1u75 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u75 RCSB]</span>
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}}
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'''Electron Transfer Complex between Horse Heart Cytochrome c and Zinc-Porphyrin Substituted Cytochrome c Peroxidase'''
'''Electron Transfer Complex between Horse Heart Cytochrome c and Zinc-Porphyrin Substituted Cytochrome c Peroxidase'''
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[[Category: Crane, B R.]]
[[Category: Crane, B R.]]
[[Category: Kang, S A.]]
[[Category: Kang, S A.]]
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[[Category: heme]]
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[[Category: Heme]]
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[[Category: protein-protein complex]]
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[[Category: Protein-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:50:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:06:15 2008''
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Revision as of 07:50, 3 May 2008

Template:STRUCTURE 1u75

Electron Transfer Complex between Horse Heart Cytochrome c and Zinc-Porphyrin Substituted Cytochrome c Peroxidase


Overview

Cytochrome c (Cc) and cytochrome c peroxidase (CcP) form an important redox pair for understanding interprotein electron transfer (ET). Measurements of ET rates from photoexcited CcP substituted with Zn porphyrin to either yeast Fe(III)Cc or horse Fe(III)Cc in crystals reveal that the molecular associations found in the respective crystal structures determine solution reactivity. Similar forward rates for yeast isozyme-1 Cc (yCc) and yCc homologue horse Cc (hCc), despite different orientations relative to CcP, suggest small-amplitude conformational gating of ET even in the crystalline state; faster back ET in the yCc compared to the hCc complex agrees with the relative coupling between redox sites predicted by the structures.

About this Structure

1U75 is a Protein complex structure of sequences from Equus caballus and Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Electron transfer between cytochrome c and cytochome c peroxidase in single crystals., Kang SA, Marjavaara PJ, Crane BR, J Am Chem Soc. 2004 Sep 8;126(35):10836-7. PMID:15339156 Page seeded by OCA on Sat May 3 10:50:22 2008

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