6m22

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Current revision (12:51, 6 November 2024) (edit) (undo)
 
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<StructureSection load='6m22' size='340' side='right'caption='[[6m22]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='6m22' size='340' side='right'caption='[[6m22]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6m22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M22 FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M22 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EZC:2-[[(2~{R})-2-butyl-6,7-bis(chloranyl)-2-cyclopentyl-1-oxidanylidene-3~{H}-inden-5-yl]oxy]ethanoic+acid'>EZC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCC3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EZC:2-[[(2~{R})-2-butyl-6,7-bis(chloranyl)-2-cyclopentyl-1-oxidanylidene-3~{H}-inden-5-yl]oxy]ethanoic+acid'>EZC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m22 OCA], [https://pdbe.org/6m22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m22 RCSB], [https://www.ebi.ac.uk/pdbsum/6m22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m22 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m22 OCA], [https://pdbe.org/6m22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m22 RCSB], [https://www.ebi.ac.uk/pdbsum/6m22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m22 ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[[https://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Corpus callosum agenesis-neuronopathy syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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==See Also==
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== Function ==
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*[[Solute carrier family 12 3D structures|Solute carrier family 12 3D structures]]
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[[https://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
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*[[Symporter 3D structures|Symporter 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, Y]]
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[[Category: Chen Y]]
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[[Category: Chi, X M]]
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[[Category: Chi XM]]
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[[Category: Li, X R]]
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[[Category: Li XR]]
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[[Category: Su, Q]]
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[[Category: Su Q]]
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[[Category: Zhang, Y Y]]
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[[Category: Zhang YY]]
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[[Category: Zhou, Q]]
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[[Category: Zhou Q]]
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[[Category: Membrane protein]]
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Current revision

KCC3 bound with DIOA

PDB ID 6m22

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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