Journal:Acta Cryst F:S2053230X24010094
From Proteopedia
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2. Regulatory Mechanisms: Our structural analysis sheds light on the functional implications of SB505124 binding, particularly its role in disrupting TGF-β signaling pathways, which are often deregulated in various cancers. | 2. Regulatory Mechanisms: Our structural analysis sheds light on the functional implications of SB505124 binding, particularly its role in disrupting TGF-β signaling pathways, which are often deregulated in various cancers. | ||
3. Therapeutic Potential: Based on our structural findings, we discuss the potential of SB505124 as a therapeutic agent in cancer treatment, providing a foundation for future drug development efforts targeting TGFβR1. | 3. Therapeutic Potential: Based on our structural findings, we discuss the potential of SB505124 as a therapeutic agent in cancer treatment, providing a foundation for future drug development efforts targeting TGFβR1. | ||
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<scene name='10/1060550/007_fig_3_new_01_png/2'>Image:007 Fig 3 New 01 PNG | <scene name='10/1060550/007_fig_3_new_01_png/2'>Image:007 Fig 3 New 01 PNG | ||
Revision as of 07:08, 13 November 2024
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