1u9s
From Proteopedia
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[[Image:1u9s.gif|left|200px]] | [[Image:1u9s.gif|left|200px]] | ||
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| - | + | {{STRUCTURE_1u9s| PDB=1u9s | SCENE= }} | |
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'''Crystal structure of the specificity domain of Ribonuclease P of the A-type''' | '''Crystal structure of the specificity domain of Ribonuclease P of the A-type''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1U9S is a [[Single protein]] structure | + | 1U9S is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Pan, T.]] | [[Category: Pan, T.]] | ||
[[Category: Xiao, Y.]] | [[Category: Xiao, Y.]] | ||
| - | [[Category: | + | [[Category: P rna]] |
| - | [[Category: | + | [[Category: Pre-trna]] |
| - | [[Category: | + | [[Category: Ribonuclease p rna]] |
| - | [[Category: | + | [[Category: Ribozyme]] |
| - | [[Category: | + | [[Category: Rnase p]] |
| - | [[Category: | + | [[Category: S-domain]] |
| - | [[Category: | + | [[Category: Specificity domain]] |
| - | [[Category: | + | [[Category: Thermus thermophilus]] |
| - | [[Category: | + | [[Category: Trna]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:56:42 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 07:56, 3 May 2008
Crystal structure of the specificity domain of Ribonuclease P of the A-type
Overview
Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.
About this Structure
1U9S is a Single protein structure. Full crystallographic information is available from OCA.
Reference
Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:15459389 Page seeded by OCA on Sat May 3 10:56:42 2008
