1xuo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search

OCA (Talk | contribs)
(New page: 200px<br /> <applet load="1xuo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xuo, resolution 1.80&Aring;" /> '''X-ray structure of ...)
Next diff →

Revision as of 18:04, 12 November 2007

Image:1xuo.gif

1xuo, resolution 1.80Å

Drag the structure with the mouse to rotate

X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution

Overview

1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1, inhibitors. The synthesis, structure, and biological evaluation of these, 1,4-diazepine-2,5-diones and related derivatives are described.

About this Structure

1XUO is a Single protein structure of sequence from Homo sapiens with MG and LA1 as ligands. Full crystallographic information is available from OCA.

Reference

1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1., Wattanasin S, Kallen J, Myers S, Guo Q, Sabio M, Ehrhardt C, Albert R, Hommel U, Weckbecker G, Welzenbach K, Weitz-Schmidt G, Bioorg Med Chem Lett. 2005 Feb 15;15(4):1217-20. PMID:15686945

Page seeded by OCA on Mon Nov 12 20:11:13 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xuo"
Personal tools