1yc5

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Current revision (00:41, 21 November 2024) (edit) (undo)
 
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yc5 OCA], [https://pdbe.org/1yc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yc5 RCSB], [https://www.ebi.ac.uk/pdbsum/1yc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yc5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yc5 OCA], [https://pdbe.org/1yc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yc5 RCSB], [https://www.ebi.ac.uk/pdbsum/1yc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yc5 ProSAT]</span></td></tr>
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</table>
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== Function ==
 
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[https://www.uniprot.org/uniprot/NPD_THEMA NPD_THEMA] NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP-ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear.<ref>PMID:17684016</ref> <ref>PMID:16905097</ref> <ref>PMID:19801667</ref>
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yc/1yc5_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yc/1yc5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>

Current revision

Sir2-p53 peptide-nicotinamide

PDB ID 1yc5

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