2e3v

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Current revision (00:53, 21 November 2024) (edit) (undo)
 
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<StructureSection load='2e3v' size='340' side='right'caption='[[2e3v]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2e3v' size='340' side='right'caption='[[2e3v]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2e3v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E3V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2e3v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E3V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2haz|2haz]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NCAM1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3v OCA], [https://pdbe.org/2e3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e3v RCSB], [https://www.ebi.ac.uk/pdbsum/2e3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e3v ProSAT], [https://www.topsan.org/Proteins/RSGI/2e3v TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3v OCA], [https://pdbe.org/2e3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e3v RCSB], [https://www.ebi.ac.uk/pdbsum/2e3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e3v ProSAT], [https://www.topsan.org/Proteins/RSGI/2e3v TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/NCAM1_HUMAN NCAM1_HUMAN]] This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3v_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Kishishita, S]]
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[[Category: Kishishita S]]
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[[Category: Liu, Z J]]
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[[Category: Liu ZJ]]
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[[Category: Nishino, A]]
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[[Category: Nishino A]]
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[[Category: Structural genomic]]
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[[Category: Saijo S]]
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[[Category: Saijo, S]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Wang BC]]
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[[Category: Wang, B C]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Cd56 antigen]]
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[[Category: Cell adhesion]]
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[[Category: Glycoprotein]]
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[[Category: Membrane protein]]
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[[Category: N-cam 1]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Ncam]]
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[[Category: Ncam-120]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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Current revision

Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4

PDB ID 2e3v

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