2gv5
From Proteopedia
(Difference between revisions)
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<StructureSection load='2gv5' size='340' side='right'caption='[[2gv5]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='2gv5' size='340' side='right'caption='[[2gv5]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2gv5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2gv5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GV5 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gv5 OCA], [https://pdbe.org/2gv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gv5 RCSB], [https://www.ebi.ac.uk/pdbsum/2gv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gv5 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gv5 OCA], [https://pdbe.org/2gv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gv5 RCSB], [https://www.ebi.ac.uk/pdbsum/2gv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gv5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
- | == Function == | ||
- | [[https://www.uniprot.org/uniprot/CDC31_YEAST CDC31_YEAST]] Functions as a component of the nuclear pore complex (NPC) and the spindle pole body (SPB) half-bridge. At the SPB, it is recruited by KAR1 and MPS3 to the SPB half-bridge and involved in the initial steps of SPB duplication. It probably plays a similar role in de novo assembly of NPCs at the nuclear envelope. Also involved in connection with the protein kinase KIC1 in the maintenance of cell morphology and integrity.<ref>PMID:8188750</ref> <ref>PMID:8070654</ref> <ref>PMID:9813095</ref> <ref>PMID:11156974</ref> <ref>PMID:12486115</ref> <ref>PMID:14504268</ref> [[https://www.uniprot.org/uniprot/SFI1_YEAST SFI1_YEAST]] Component of the spindle pole body (SPB) half-bridge involved in the initial steps of SPB duplication.<ref>PMID:10455233</ref> <ref>PMID:14504268</ref> <ref>PMID:16785321</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gv5_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gv5_consurf.spt"</scriptWhenChecked> | ||
- | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Atcc 18824]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Conduit | + | [[Category: Saccharomyces cerevisiae]] |
- | [[Category: Kilmartin | + | [[Category: Conduit PT]] |
- | [[Category: Li | + | [[Category: Kilmartin JV]] |
- | [[Category: Robinson | + | [[Category: Li S]] |
- | [[Category: Sandercock | + | [[Category: Robinson CV]] |
- | [[Category: Williams | + | [[Category: Sandercock AM]] |
- | + | [[Category: Williams RL]] | |
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Current revision
crystal structure of Sfi1p/Cdc31p complex
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