2qs9

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Current revision (01:22, 21 November 2024) (edit) (undo)
 
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<StructureSection load='2qs9' size='340' side='right'caption='[[2qs9]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
<StructureSection load='2qs9' size='340' side='right'caption='[[2qs9]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QS9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QS9 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [https://pdbe.org/2qs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [https://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qs9 ProSAT], [https://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [https://pdbe.org/2qs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [https://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qs9 ProSAT], [https://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/RBBP9_HUMAN RBBP9_HUMAN]] May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qs9_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qs9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Chen, C X]]
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[[Category: Chen CX]]
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[[Category: Cunningham, K]]
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[[Category: Cunningham K]]
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[[Category: Hunt, J F]]
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[[Category: Hunt JF]]
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[[Category: Kuzin, A]]
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[[Category: Kuzin A]]
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[[Category: Maglaqui, M]]
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[[Category: Maglaqui M]]
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[[Category: Montelione, G T]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Owens L]]
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[[Category: Owens, L]]
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[[Category: Seetharaman J]]
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[[Category: Seetharaman, J]]
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[[Category: Su M]]
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[[Category: Su, M]]
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[[Category: Tong L]]
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[[Category: Tong, L]]
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[[Category: Vorobiev SM]]
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[[Category: Vorobiev, S M]]
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[[Category: Xiao R]]
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[[Category: Xiao, R]]
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[[Category: Alternative splicing]]
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[[Category: B5t overexpressed gene protein]]
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[[Category: Bog]]
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[[Category: Cytoplasm]]
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[[Category: Hr2978]]
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[[Category: Nesg]]
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[[Category: Nucleus]]
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[[Category: Phosphorylation]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Rbbp10]]
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[[Category: Rbbp9]]
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[[Category: Retinoblastoma-binding protein 10]]
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[[Category: Retinoblastoma-binding protein 9]]
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[[Category: Structural protein]]
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Current revision

Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978

PDB ID 2qs9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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