2z0q

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Current revision (01:33, 21 November 2024) (edit) (undo)
 
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<StructureSection load='2z0q' size='340' side='right'caption='[[2z0q]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='2z0q' size='340' side='right'caption='[[2z0q]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z0q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0Q OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Z0Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z0q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z0Q FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2z0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0q OCA], [http://pdbe.org/2z0q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z0q RCSB], [http://www.ebi.ac.uk/pdbsum/2z0q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z0q ProSAT], [http://www.topsan.org/Proteins/RSGI/2z0q TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0q OCA], [https://pdbe.org/2z0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z0q RCSB], [https://www.ebi.ac.uk/pdbsum/2z0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z0q ProSAT], [https://www.topsan.org/Proteins/RSGI/2z0q TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/ARHG3_MOUSE ARHG3_MOUSE]] Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z0q_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z0q_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 2z0q" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2z0q" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Kato-Murayama, M]]
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[[Category: Kato-Murayama M]]
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[[Category: Murayama, K]]
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[[Category: Murayama K]]
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[[Category: Structural genomic]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Terada T]]
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[[Category: Terada, T]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Dh-ph domain]]
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[[Category: Guanine-nucleotide releasing factor]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of DH-PH domain of RhoGEF3(Xpln)

PDB ID 2z0q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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