3ehq

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Current revision (01:46, 21 November 2024) (edit) (undo)
 
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<StructureSection load='3ehq' size='340' side='right'caption='[[3ehq]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
<StructureSection load='3ehq' size='340' side='right'caption='[[3ehq]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ehq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EHQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ehq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EHQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ehr|3ehr]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OSTF1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ehq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ehq OCA], [https://pdbe.org/3ehq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ehq RCSB], [https://www.ebi.ac.uk/pdbsum/3ehq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ehq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ehq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ehq OCA], [https://pdbe.org/3ehq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ehq RCSB], [https://www.ebi.ac.uk/pdbsum/3ehq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ehq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/OSTF1_HUMAN OSTF1_HUMAN]] Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.<ref>PMID:10092216</ref>
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[https://www.uniprot.org/uniprot/OSTF1_HUMAN OSTF1_HUMAN] Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.<ref>PMID:10092216</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/3ehq_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/3ehq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gao, Y]]
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[[Category: Gao Y]]
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[[Category: Niu, L]]
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[[Category: Niu L]]
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[[Category: Teng, M]]
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[[Category: Teng M]]
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[[Category: Tong, S]]
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[[Category: Tong S]]
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[[Category: Zhang, X]]
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[[Category: Zhang X]]
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[[Category: Zhou, H]]
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[[Category: Zhou H]]
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[[Category: Zhu, Z]]
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[[Category: Zhu Z]]
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[[Category: Ank repeat]]
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[[Category: Ankyrin repeat]]
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[[Category: Beta barrel]]
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[[Category: Cytoplasm]]
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[[Category: Helix-turn-helix]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Sh3]]
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[[Category: Sh3 domain]]
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[[Category: Signaling protein]]
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Current revision

Crystal Structure of Human Osteoclast Stimulating Factor

PDB ID 3ehq

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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