3kwo

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Current revision (02:02, 21 November 2024) (edit) (undo)
 
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==Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni==
==Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni==
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<StructureSection load='3kwo' size='340' side='right'caption='[[3kwo]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
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<StructureSection load='3kwo' size='340' side='right'caption='[[3kwo]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kwo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KWO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KWO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kwo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KWO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.985&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3kwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kwo OCA], [http://pdbe.org/3kwo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kwo RCSB], [http://www.ebi.ac.uk/pdbsum/3kwo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kwo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kwo OCA], [https://pdbe.org/3kwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kwo RCSB], [https://www.ebi.ac.uk/pdbsum/3kwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kwo ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/DPS_CAMJE DPS_CAMJE]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (Probable). Does not bind DNA.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/3kwo_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/3kwo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Camje]]
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[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, W]]
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[[Category: Anderson W]]
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[[Category: Structural genomic]]
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[[Category: Gu M]]
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[[Category: Gu, M]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A]]
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[[Category: Kim Y]]
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[[Category: Kim, Y]]
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[[Category: Papazisi L]]
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[[Category: Papazisi, L]]
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[[Category: Alpha-helix]]
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[[Category: Bacterial ferritin fold]]
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[[Category: Csgid]]
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[[Category: Cytoplasm]]
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[[Category: Iron]]
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[[Category: Iron storage]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni

PDB ID 3kwo

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