3uw0
From Proteopedia
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== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/A1JJ76_YERE8 A1JJ76_YERE8] | [https://www.uniprot.org/uniprot/A1JJ76_YERE8 A1JJ76_YERE8] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Pectin methylesterases (PMEs) are family 8 carbohydrate esterases (CE8s) which remove the methyl group from methylesterified galacturonic acid (GalA) residues within pectin. Although the role of pectinases such as PMEs within dedicated phytopathogens has been well established, the significance of homologous enzymes found within the genomes of human enteropathogens remains to be determined. Presented here is the low-resolution (3.5 A) structure of the CE8 from Yersinia enterocolitica (YeCE8). The high degree of structural conservation in the topology of the active-site cleft and catalytic apparatus that is shared with a characterized PME from a bacterial phytopathogen (i) indicates that YeCE8 is active on methylated pectin and (ii) highlights a more prominent role for pectin utilization in Yersinia than in other enteropathogenic species. | ||
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| + | Structure of a pectin methylesterase from Yersinia enterocolitica.,Boraston AB, Abbott DW Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):129-33., Epub 2012 Jan 21. PMID:22297983<ref>PMID:22297983</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 3uw0" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Methylesterase 3D structures|Methylesterase 3D structures]] | *[[Methylesterase 3D structures|Methylesterase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Pectin methylesterase from Yersinia enterocolitica
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