4mae
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mae]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylacidiphilum_fumariolicum_SolV Methylacidiphilum fumariolicum SolV]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MAE FirstGlance]. <br> | <table><tr><td colspan='2'>[[4mae]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylacidiphilum_fumariolicum_SolV Methylacidiphilum fumariolicum SolV]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MAE FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=CE:CERIUM+(III)+ION'>CE</scene>, <scene name='pdbligand=PQQ:PYRROLOQUINOLINE+QUINONE'>PQQ</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=CE:CERIUM+(III)+ION'>CE</scene>, <scene name='pdbligand=PQQ:PYRROLOQUINOLINE+QUINONE'>PQQ</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mae OCA], [https://pdbe.org/4mae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mae RCSB], [https://www.ebi.ac.uk/pdbsum/4mae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mae ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mae OCA], [https://pdbe.org/4mae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mae RCSB], [https://www.ebi.ac.uk/pdbsum/4mae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mae ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ | + | [https://www.uniprot.org/uniprot/XOXF_METFB XOXF_METFB] Catalyzes the oxidation of methanol to formaldehyde or formate in the presence of lanthanides (Ln). Is a key enzyme in methane/methanol metabolism, allowing M.fumariolicum to grow on methane as the sole carbon and energy source. Can also act on other primary alcohols in vitro, such as ethanol, 1-propanol, 1-butanol, and 1-hexanol, but is not able to oxidize secondary alcohols and acetaldehyde (PubMed:24034209). Uses a specific cytochrome cL, encoded by the adjacent gene in the locus, as electron acceptor (By similarity).[UniProtKB:C5B120]<ref>PMID:24034209</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Methanol dehydrogenase from Methylacidiphilum fumariolicum SolV
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