5jyh
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5jyh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hadrurus_gertschi Hadrurus gertschi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JYH FirstGlance]. <br> | <table><tr><td colspan='2'>[[5jyh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hadrurus_gertschi Hadrurus gertschi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JYH FirstGlance]. <br> | ||
| - | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyh OCA], [https://pdbe.org/5jyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jyh RCSB], [https://www.ebi.ac.uk/pdbsum/5jyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyh OCA], [https://pdbe.org/5jyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jyh RCSB], [https://www.ebi.ac.uk/pdbsum/5jyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/KBX3_HOFGE KBX3_HOFGE] Has antibacterial activity against B.subtilis, but not against S.aureus. Also has hemolytic and cytolytic activities.<ref>PMID:18030427</ref> Blocks Kv1.1/KCNA1 (IC(50)=185 nM) potassium channels. Shows a weak hemolytic activity.<ref>PMID:18030427</ref> <ref>PMID:27314815</ref> | + | [https://www.uniprot.org/uniprot/KBX3_HOFGE KBX3_HOFGE] Has antibacterial activity against B.subtilis, but not against S.aureus. Also has hemolytic and cytolytic activities. Since cell lysis occurs at the tested concentrations, observation of activity on potassium channels is impossible.<ref>PMID:18030427</ref> Blocks Kv1.1/KCNA1 (IC(50)=185 nM) potassium channels. Shows a weak hemolytic activity.<ref>PMID:18030427</ref> <ref>PMID:27314815</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi
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