6omt
From Proteopedia
(Difference between revisions)
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<StructureSection load='6omt' size='340' side='right'caption='[[6omt]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='6omt' size='340' side='right'caption='[[6omt]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6omt]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6omt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OMT FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.052Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6omt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6omt OCA], [https://pdbe.org/6omt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6omt RCSB], [https://www.ebi.ac.uk/pdbsum/6omt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6omt ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GAG_HV1N5 GAG_HV1N5] Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu. Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers. p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6omt" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6omt" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]] | ||
| + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Huang | + | [[Category: Huang P]] |
| - | [[Category: Summers | + | [[Category: Summers BJ]] |
| - | [[Category: Xiong | + | [[Category: Xiong Y]] |
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Current revision
HIV-1 capsid hexamer R18D mutant
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