7egy
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='7egy' size='340' side='right'caption='[[7egy]], [[Resolution|resolution]] 4.20Å' scene=''> | <StructureSection load='7egy' size='340' side='right'caption='[[7egy]], [[Resolution|resolution]] 4.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EGY FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.201Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.201Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7egy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7egy OCA], [https://pdbe.org/7egy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7egy RCSB], [https://www.ebi.ac.uk/pdbsum/7egy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7egy ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7egy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7egy OCA], [https://pdbe.org/7egy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7egy RCSB], [https://www.ebi.ac.uk/pdbsum/7egy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7egy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/Q991S8_9FLAV Q991S8_9FLAV] Acts as a cofactor for the NS3 protease activity.[ARBA:ARBA00023576] Leader cysteine autoprotease that cleaves itself from the nascent polyprotein during translation of the viral mRNA. Once released, plays a role in the inhibition of host innate immune response by interacting with host IRF3 and inducing its proteasomal degradation.[ARBA:ARBA00023578] Packages viral RNA to form a viral nucleocapsid and thereby protects viral RNA. Also plays a role in transcription regulation. Protects the incoming virus against IFN-induced effectors.[ARBA:ARBA00034097] Plays a role in the regulation of viral RNA replication.[ARBA:ARBA00023574] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Hog cholera virus strain 'Chinese vaccine, Wuhan']] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ru QX]] | [[Category: Ru QX]] | ||
Current revision
Recombinant head-to-tail dimeric E2 protein
| |||||||||||
