7fy0
From Proteopedia
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| - | ==Crystal Structure of human FABP5 in complex with (2R)-1-[(3,5-dichloro-2-phenylphenyl)carbamoyl]pyrrolidine-2-carboxylic acid== | + | ==Crystal Structure of human FABP5 in complex with (2R)-1-[(3,5-dichloro-2-phenylphenyl)carbamoyl]pyrrolidine-2-carboxylic acid, i.e. SMILES c1(cc(cc(c1c1ccccc1)Cl)Cl)NC(=O)N1CCC[C@@H]1C(=O)O with IC50=18 microM== |
<StructureSection load='7fy0' size='340' side='right'caption='[[7fy0]], [[Resolution|resolution]] 1.34Å' scene=''> | <StructureSection load='7fy0' size='340' side='right'caption='[[7fy0]], [[Resolution|resolution]] 1.34Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7fy0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FY0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fy0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FY0 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.34Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.34Å</td></tr> | ||
| - | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UOF:1-[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UOF:(2~{R})-1-[[3,5-bis(chloranyl)-2-phenyl-phenyl]carbamoyl]pyrrolidine-2-carboxylic+acid'>UOF</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fy0 OCA], [https://pdbe.org/7fy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fy0 RCSB], [https://www.ebi.ac.uk/pdbsum/7fy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fy0 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fy0 OCA], [https://pdbe.org/7fy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fy0 RCSB], [https://www.ebi.ac.uk/pdbsum/7fy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fy0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Revision as of 06:19, 21 November 2024
Crystal Structure of human FABP5 in complex with (2R)-1-[(3,5-dichloro-2-phenylphenyl)carbamoyl]pyrrolidine-2-carboxylic acid, i.e. SMILES c1(cc(cc(c1c1ccccc1)Cl)Cl)NC(=O)N1CCC[C@@H]1C(=O)O with IC50=18 microM
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Categories: Homo sapiens | Large Structures | Benz J | Ehler A | Obst U | Obst-Sander U | Rudolph MG
