7fzp
From Proteopedia
(Difference between revisions)
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| - | ==Crystal Structure of human FABP4 in complex with 6-[(4-chlorophenyl)methylsulfanylmethyl]-2-sulfanylidene-1H-pyrimidin-4-one== | + | ==Crystal Structure of human FABP4 in complex with 6-[(4-chlorophenyl)methylsulfanylmethyl]-2-sulfanylidene-1H-pyrimidin-4-one, i.e. SMILES c1c(ccc(c1)Cl)CSCC1=CC(=O)NC(=S)N1 with IC50=0.890 microM== |
<StructureSection load='7fzp' size='340' side='right'caption='[[7fzp]], [[Resolution|resolution]] 1.12Å' scene=''> | <StructureSection load='7fzp' size='340' side='right'caption='[[7fzp]], [[Resolution|resolution]] 1.12Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7fzp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FZP FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fzp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FZP FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | ||
| - | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WHI:6- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WHI:6-[(4-chlorophenyl)methylsulfanylmethyl]-2-sulfanylidene-1~{H}-pyrimidin-4-one'>WHI</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fzp OCA], [https://pdbe.org/7fzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fzp RCSB], [https://www.ebi.ac.uk/pdbsum/7fzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fzp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fzp OCA], [https://pdbe.org/7fzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fzp RCSB], [https://www.ebi.ac.uk/pdbsum/7fzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fzp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Current revision
Crystal Structure of human FABP4 in complex with 6-[(4-chlorophenyl)methylsulfanylmethyl]-2-sulfanylidene-1H-pyrimidin-4-one, i.e. SMILES c1c(ccc(c1)Cl)CSCC1=CC(=O)NC(=S)N1 with IC50=0.890 microM
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Categories: Homo sapiens | Large Structures | Benz J | Ehler A | Obst U | Rudolph MG | Wichmann J
