7g1o
From Proteopedia
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| - | ==Crystal Structure of human FABP4 in complex with 4-chloro-2,5-dimethyl-N-(2-methylpyrazol-3-yl)benzenesulfonamide== | + | ==Crystal Structure of human FABP4 in complex with 4-chloro-2,5-dimethyl-N-(2-methylpyrazol-3-yl)benzenesulfonamide, i.e. SMILES S(=O)(=O)(NC1=CC=NN1C)c1cc(c(cc1C)Cl)C with IC50=0.146 microM== |
<StructureSection load='7g1o' size='340' side='right'caption='[[7g1o]], [[Resolution|resolution]] 1.12Å' scene=''> | <StructureSection load='7g1o' size='340' side='right'caption='[[7g1o]], [[Resolution|resolution]] 1.12Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7g1o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G1O FirstGlance]. <br> | <table><tr><td colspan='2'>[[7g1o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G1O FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | ||
| - | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WP8:4- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WP8:4-chloranyl-2,5-dimethyl-~{N}-(2-methylpyrazol-3-yl)benzenesulfonamide'>WP8</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g1o OCA], [https://pdbe.org/7g1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g1o RCSB], [https://www.ebi.ac.uk/pdbsum/7g1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g1o ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g1o OCA], [https://pdbe.org/7g1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g1o RCSB], [https://www.ebi.ac.uk/pdbsum/7g1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g1o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Revision as of 06:23, 21 November 2024
Crystal Structure of human FABP4 in complex with 4-chloro-2,5-dimethyl-N-(2-methylpyrazol-3-yl)benzenesulfonamide, i.e. SMILES S(=O)(=O)(NC1=CC=NN1C)c1cc(c(cc1C)Cl)C with IC50=0.146 microM
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Categories: Homo sapiens | Large Structures | Benz J | Brunner M | Ehler A | Obst U | Rudolph MG
