7n1z
From Proteopedia
(Difference between revisions)
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<StructureSection load='7n1z' size='340' side='right'caption='[[7n1z]]' scene=''> | <StructureSection load='7n1z' size='340' side='right'caption='[[7n1z]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N1Z FirstGlance]. <br> |
| - | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> |
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n1z OCA], [https://pdbe.org/7n1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n1z RCSB], [https://www.ebi.ac.uk/pdbsum/7n1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n1z ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n1z OCA], [https://pdbe.org/7n1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n1z RCSB], [https://www.ebi.ac.uk/pdbsum/7n1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n1z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/CA1A_CONPE CA1A_CONPE] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian nAChRs (alpha-3/beta-2 > alpha-7 > alpha-3/beta-4).<ref>PMID:10545176</ref> <ref>PMID:8068627</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Conus pennaceus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Conibear AC]] | [[Category: Conibear AC]] | ||
[[Category: Lee HS]] | [[Category: Lee HS]] | ||
[[Category: Rosengren KJ]] | [[Category: Rosengren KJ]] | ||
Current revision
NMR structure of native PnIA
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