3hhf

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Current revision (06:17, 27 November 2024) (edit) (undo)
 
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<StructureSection load='3hhf' size='340' side='right'caption='[[3hhf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3hhf' size='340' side='right'caption='[[3hhf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hhf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimi Neimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hhf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_B Neisseria meningitidis serogroup B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hhg|3hhg]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CrgA, NMB1856 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhf OCA], [https://pdbe.org/3hhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhf RCSB], [https://www.ebi.ac.uk/pdbsum/3hhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhf OCA], [https://pdbe.org/3hhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhf RCSB], [https://www.ebi.ac.uk/pdbsum/3hhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhf ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CRGA_NEIMB CRGA_NEIMB] Regulatory protein that activates transcription of mdaB, encoding a NADPH:quinone oxidoreductase, and represses its own transcription (PubMed:15866928). Under the same experimental conditions, no regulation of transcription of pilus and capsule genes is detected (PubMed:15866928).<ref>PMID:15866928</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/3hhf_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/3hhf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Neimi]]
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[[Category: Neisseria meningitidis serogroup B]]
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[[Category: OPPF, Oxford Protein Production Facility]]
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[[Category: Owens RJ]]
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[[Category: Owens, R J]]
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[[Category: Ren J]]
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[[Category: Ren, J]]
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[[Category: Sainsbury S]]
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[[Category: Sainsbury, S]]
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[[Category: Stuart DI]]
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[[Category: Stuart, D I]]
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[[Category: Dna-binding]]
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[[Category: Lysr]]
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[[Category: Neisseria meningitidi]]
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[[Category: Oppf]]
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[[Category: Oxford protein production facility]]
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[[Category: Structural genomic]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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Current revision

Structure of CrgA regulatory domain, a LysR-type transcriptional regulator from Neisseria meningitidis.

PDB ID 3hhf

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