4o0y

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Current revision (07:15, 27 November 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4o0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O0Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[4o0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O0Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2OO:4-[1-(4-AMINO-1,3,5-TRIAZIN-2-YL)-2-(ETHYLAMINO)-1H-BENZIMIDAZOL-6-YL]-2-METHYLBUT-3-YN-2-OL'>2OO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2OO:4-[1-(4-AMINO-1,3,5-TRIAZIN-2-YL)-2-(ETHYLAMINO)-1H-BENZIMIDAZOL-6-YL]-2-METHYLBUT-3-YN-2-OL'>2OO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o0y OCA], [https://pdbe.org/4o0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o0y RCSB], [https://www.ebi.ac.uk/pdbsum/4o0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o0y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o0y OCA], [https://pdbe.org/4o0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o0y RCSB], [https://www.ebi.ac.uk/pdbsum/4o0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o0y ProSAT]</span></td></tr>
</table>
</table>

Current revision

Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors

PDB ID 4o0y

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