8k7r

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Current revision (06:13, 4 December 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8k7r is ON HOLD until Paper Publication
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==Human Fc epsilon RI in complex with hIgE Fc (TMD disordered)==
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<StructureSection load='8k7r' size='340' side='right'caption='[[8k7r]], [[Resolution|resolution]] 3.56&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8k7r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K7R FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.56&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k7r OCA], [https://pdbe.org/8k7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k7r RCSB], [https://www.ebi.ac.uk/pdbsum/8k7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k7r ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FCERA_HUMAN FCERA_HUMAN] Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ohto U]]
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[[Category: Shimizu T]]
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[[Category: Yui M]]
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[[Category: Zhang Z]]

Current revision

Human Fc epsilon RI in complex with hIgE Fc (TMD disordered)

PDB ID 8k7r

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