9dzq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM structure of the human antibodies PIV3HN-05 and PIV3HN-13 in complex with the parainfluenza virus hemagglutinin-neuraminidase protein== | |
| - | + | <StructureSection load='9dzq' size='340' side='right'caption='[[9dzq]], [[Resolution|resolution]] 3.57Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9dzq]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_respirovirus_3 Human respirovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DZQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DZQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.57Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dzq OCA], [https://pdbe.org/9dzq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dzq RCSB], [https://www.ebi.ac.uk/pdbsum/9dzq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dzq ProSAT]</span></td></tr> |
| - | [[Category: Miller | + | </table> |
| - | [[Category: Mousa | + | == Function == |
| + | [https://www.uniprot.org/uniprot/Q81080_PI3H4 Q81080_PI3H4] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.[ARBA:ARBA00025476] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Human respirovirus 3]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Miller RJ]] | ||
| + | [[Category: Mousa JJ]] | ||
Current revision
CryoEM structure of the human antibodies PIV3HN-05 and PIV3HN-13 in complex with the parainfluenza virus hemagglutinin-neuraminidase protein
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