5rjj
From Proteopedia
(Difference between revisions)
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<StructureSection load='5rjj' size='340' side='right'caption='[[5rjj]], [[Resolution|resolution]] 1.15Å' scene=''> | <StructureSection load='5rjj' size='340' side='right'caption='[[5rjj]], [[Resolution|resolution]] 1.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5RJJ FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.151Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.151Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HH8:4-bromanyl-1,8-naphthyridine'>HH8</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HH8:4-bromanyl-1,8-naphthyridine'>HH8</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rjj OCA], [https://pdbe.org/5rjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rjj RCSB], [https://www.ebi.ac.uk/pdbsum/5rjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rjj ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rjj OCA], [https://pdbe.org/5rjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rjj RCSB], [https://www.ebi.ac.uk/pdbsum/5rjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rjj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref> | ||
==See Also== | ==See Also== | ||
*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]] | *[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aimon A]] | [[Category: Aimon A]] | ||
Current revision
PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00023833
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Categories: Large Structures | Aimon A | Arrowsmith CH | Biggin PC | Bountra C | Douangamath A | Edwards A | Grosjean H | Koekemoer L | Krojer T | Talon R | Von Delft F
