1ut7
From Proteopedia
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'''STRUCTURE OF THE CONSERVED DOMAIN OF ANAC, A MEMBER OF THE NAC FAMILY OF TRANSCRIPTION FACTORS''' | '''STRUCTURE OF THE CONSERVED DOMAIN OF ANAC, A MEMBER OF THE NAC FAMILY OF TRANSCRIPTION FACTORS''' | ||
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[[Category: Olsen, A N.]] | [[Category: Olsen, A N.]] | ||
[[Category: Skriver, K.]] | [[Category: Skriver, K.]] | ||
| - | [[Category: | + | [[Category: Abscisic acid response]] |
| - | [[Category: | + | [[Category: Arabidopsis thaliana]] |
| - | [[Category: | + | [[Category: Crystal structure]] |
| - | [[Category: | + | [[Category: Dna binding]] |
| - | [[Category: | + | [[Category: Nac domain]] |
| - | [[Category: | + | [[Category: Transcription]] |
| - | [[Category: | + | [[Category: Transcription factor]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:39:24 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 08:39, 3 May 2008
STRUCTURE OF THE CONSERVED DOMAIN OF ANAC, A MEMBER OF THE NAC FAMILY OF TRANSCRIPTION FACTORS
Overview
The structure of the DNA-binding NAC domain of Arabidopsis ANAC (abscisic-acid-responsive NAC) has been determined by X-ray crystallography to 1.9A resolution (Protein Data Bank codes 1UT4 and 1UT7). This is the first structure determined for a member of the NAC family of plant-specific transcriptional regulators. NAC proteins are characterized by their conserved N-terminal NAC domains that can bind both DNA and other proteins. NAC proteins are involved in developmental processes, including formation of the shoot apical meristem, floral organs and lateral shoots, as well as in plant hormonal control and defence. The NAC domain does not possess a classical helix-turn-helix motif; instead it reveals a new transcription factor fold consisting of a twisted beta-sheet surrounded by a few helical elements. The functional dimer formed by the NAC domain was identified in the structure, which will serve as a structural template for understanding NAC protein function at the molecular level.
About this Structure
1UT7 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors., Ernst HA, Olsen AN, Larsen S, Lo Leggio L, EMBO Rep. 2004 Mar;5(3):297-303. PMID:15083810 Page seeded by OCA on Sat May 3 11:39:24 2008
