8s7g
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of Pseudomonas aeruginosa Recombinase A (RecA) in complex with LexAS125A mutant== | |
| - | + | <StructureSection load='8s7g' size='340' side='right'caption='[[8s7g]], [[Resolution|resolution]] 3.43Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8s7g]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S7G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.43Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s7g OCA], [https://pdbe.org/8s7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s7g RCSB], [https://www.ebi.ac.uk/pdbsum/8s7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s7g ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/LEXA_PSEAE LEXA_PSEAE] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. |
| - | [[Category: De Felice | + | __TOC__ |
| - | [[Category: Jakobi | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Catalano C]] | ||
| + | [[Category: Cendron L]] | ||
| + | [[Category: De Felice S]] | ||
| + | [[Category: Huber ST]] | ||
| + | [[Category: Jakobi AJ]] | ||
| + | [[Category: Vascon F]] | ||
Current revision
Cryo-EM structure of Pseudomonas aeruginosa Recombinase A (RecA) in complex with LexAS125A mutant
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