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1yho
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(New page: 200px<br /> <applet load="1yho" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yho" /> '''Solution structure of human dihydrofolate r...)
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Revision as of 18:13, 12 November 2007
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Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
Disease
Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[126060]
About this Structure
1YHO is a Single protein structure of sequence from Homo sapiens with NDP and TRR as ligands. Active as Dihydrofolate reductase, with EC number 1.5.1.3 Full crystallographic information is available from OCA.
Reference
Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH., Kovalevskaya NV, Smurnyy YD, Polshakov VI, Birdsall B, Bradbury AF, Frenkiel T, Feeney J, J Biomol NMR. 2005 Sep;33(1):69-72. PMID:16222560
Page seeded by OCA on Mon Nov 12 20:19:56 2007
