8rib

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Current revision (06:15, 29 January 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8rib is ON HOLD until Paper Publication
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==N-terminal domain of Trypanosoma brucei PEX14 in complex with a pyrazolo-pyrazolo[4,3-c]pyridin-3-yl compound showing a novel binding pose==
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<StructureSection load='8rib' size='340' side='right'caption='[[8rib]], [[Resolution|resolution]] 1.13&Aring;' scene=''>
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Authors: Napolitano, V., Janna Olmos, J., Popowicz, G.M., Dubin, G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8rib]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RIB FirstGlance]. <br>
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Description: N-terminal domain of Trypanosoma brucei PEX14 in complex with a pyrazolo-pyrazolo[4,3-c]pyridin-3-yl compound showing a novel binding pose
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.126&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OJN:1-(2-azanylethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-[(4-methylsulfanylphenyl)methyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide'>OJN</scene></td></tr>
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[[Category: Janna Olmos, J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rib OCA], [https://pdbe.org/8rib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rib RCSB], [https://www.ebi.ac.uk/pdbsum/8rib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rib ProSAT]</span></td></tr>
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[[Category: Popowicz, G.M]]
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</table>
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[[Category: Napolitano, V]]
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== Function ==
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[[Category: Dubin, G]]
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[https://www.uniprot.org/uniprot/Q8IEW2_TRYBB Q8IEW2_TRYBB]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Trypanosoma brucei brucei]]
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[[Category: Dubin G]]
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[[Category: Janna Olmos J]]
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[[Category: Napolitano V]]
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[[Category: Popowicz GM]]

Current revision

N-terminal domain of Trypanosoma brucei PEX14 in complex with a pyrazolo-pyrazolo[4,3-c]pyridin-3-yl compound showing a novel binding pose

PDB ID 8rib

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