8vvx

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Current revision (06:22, 5 February 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8vvx is ON HOLD until Paper Publication
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==Human Aquaporin 2 from 2D electron diffraction data==
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<StructureSection load='8vvx' size='340' side='right'caption='[[8vvx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Vahedi-Faridi, A., Lodowski, D.T., Engel, A., Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8vvx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VVX FirstGlance]. <br>
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Description: Human Aquaporin 2 from 2D electron diffraction data
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vvx OCA], [https://pdbe.org/8vvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vvx RCSB], [https://www.ebi.ac.uk/pdbsum/8vvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vvx ProSAT]</span></td></tr>
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[[Category: Engel, A]]
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</table>
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[[Category: Transcontinental Em Initiative For Membrane Protein Structure (Temimps)]]
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== Disease ==
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[[Category: Vahedi-Faridi, A]]
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[https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Lodowski, D.T]]
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== Function ==
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[https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Engel A]]
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[[Category: Lodowski DT]]
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[[Category: Vahedi-Faridi A]]

Current revision

Human Aquaporin 2 from 2D electron diffraction data

PDB ID 8vvx

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