8x0p
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Tyrosine decarboxylase in complex with the cofactor PLP and inhibitor carbidopa== | |
| - | + | <StructureSection load='8x0p' size='340' side='right'caption='[[8x0p]], [[Resolution|resolution]] 3.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8x0p]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Papaver_somniferum Papaver somniferum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X0P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=142:CARBIDOPA'>142</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x0p OCA], [https://pdbe.org/8x0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x0p RCSB], [https://www.ebi.ac.uk/pdbsum/8x0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x0p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TYDC2_PAPSO TYDC2_PAPSO] Marginally higher substrate specificity for L-DOPA over L-tyrosine. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Papaver somniferum]] | ||
| + | [[Category: Wang H]] | ||
| + | [[Category: Yao M]] | ||
| + | [[Category: Yu J]] | ||
Current revision
Crystal structure of Tyrosine decarboxylase in complex with the cofactor PLP and inhibitor carbidopa
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