We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

9hnw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "9hnw" [edit=sysop:move=sysop])
Current revision (06:28, 12 February 2025) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9hnw is ON HOLD
+
==USP1-UAF1 bound to Lys63-linked diubiquitin==
-
 
+
<StructureSection load='9hnw' size='340' side='right'caption='[[9hnw]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
-
Authors: Keijzer, N., Sakoltchik, J., Sixma, T.K.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9hnw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HNW FirstGlance]. <br>
-
Description: USP1-UAF1 bound to Lys63-linked diubiquitin
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.04&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=DAB:2,4-DIAMINOBUTYRIC+ACID'>DAB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
[[Category: Keijzer, N]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hnw OCA], [https://pdbe.org/9hnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hnw RCSB], [https://www.ebi.ac.uk/pdbsum/9hnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hnw ProSAT]</span></td></tr>
-
[[Category: Sixma, T.K]]
+
</table>
-
[[Category: Sakoltchik, J]]
+
== Function ==
 +
[https://www.uniprot.org/uniprot/UBP1_HUMAN UBP1_HUMAN] Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335). Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995, PubMed:20147293). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029).<ref>PMID:15694335</ref> <ref>PMID:16531995</ref> <ref>PMID:18082604</ref> <ref>PMID:20147293</ref> <ref>PMID:26388029</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Keijzer N]]
 +
[[Category: Sakoltchik J]]
 +
[[Category: Sixma TK]]

Current revision

USP1-UAF1 bound to Lys63-linked diubiquitin

PDB ID 9hnw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9hnw"
Personal tools