9e99
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM reconstruction of Escherichia phage N4 capsid== | |
| + | <StructureSection load='9e99' size='340' side='right'caption='[[9e99]], [[Resolution|resolution]] 2.45Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[9e99]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_N4 Escherichia phage N4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9E99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9E99 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.45Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9e99 OCA], [https://pdbe.org/9e99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9e99 RCSB], [https://www.ebi.ac.uk/pdbsum/9e99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9e99 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAPSD_BPN4 CAPSD_BPN4] Assembles, to form an icosahedral capsid with a T=9 symmetry, about 60 nm in diameter, and consisting of 535 capsid proteins.<ref>PMID:18374942</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Coliphage N4 is a representative species of the Schitoviridae family of bacteriophages. Originally structurally studied in 2008, the capsid structure was solved to 14 A to reveal an interesting arrangement of Ig-like decoration proteins across the surface of the capsid. Herein, we present a high-resolution N4 structure, reporting a 2.45 A map of the capsid obtained via single particle cryogenic-electron microscopy. Structural analysis of the major capsid proteins (MCPs) and decoration proteins (gp56 and gp17) of phage N4 reveals a pattern of interactions across the capsid that are mediated by structurally homologous domains of gp17. In this study, an analysis of the complex interface contacts allows us to confirm that the gp17 Ig-like decoration proteins of N4 are likely employed by the virus to increase the capsid's structural integrity. | ||
| - | + | Atlas of Interactions Between Decoration Proteins and Major Capsid Proteins of Coliphage N4.,McJarrow-Keller K, Eruera AR, Crowe AJM, Kumaran R, Hyun J, Bostina M Viruses. 2024 Dec 26;17(1):19. doi: 10.3390/v17010019. PMID:39861808<ref>PMID:39861808</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: | + | <div class="pdbe-citations 9e99" style="background-color:#fffaf0;"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: Hyun | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Escherichia phage N4]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bostina M]] | ||
| + | [[Category: Eruera A]] | ||
| + | [[Category: Hyun JK]] | ||
| + | [[Category: McJarrow-Keller K]] | ||
Current revision
Cryo-EM reconstruction of Escherichia phage N4 capsid
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