8w6w

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Current revision (07:58, 5 March 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8w6w is ON HOLD until Paper Publication
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==Crystal Structure of C-terminal domain of nucleocapsid protein from SARS-CoV-2 in complex with ampicillin==
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<StructureSection load='8w6w' size='340' side='right'caption='[[8w6w]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Dhaka, P., Mahto, J.K., Tomar, S., Kumar, P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8w6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8W6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8W6W FirstGlance]. <br>
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Description: Crystal Structure of C-terminal domain of nucleocapsid protein from SARS-CoV-2 in complex with ampicillin
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIC:(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>AIC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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[[Category: Kumar, P]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8w6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8w6w OCA], [https://pdbe.org/8w6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8w6w RCSB], [https://www.ebi.ac.uk/pdbsum/8w6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8w6w ProSAT]</span></td></tr>
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[[Category: Tomar, S]]
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</table>
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[[Category: Mahto, J.K]]
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== Function ==
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[[Category: Dhaka, P]]
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[https://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Severe acute respiratory syndrome coronavirus 2]]
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[[Category: Dhaka P]]
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[[Category: Kumar P]]
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[[Category: Mahto JK]]
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[[Category: Tomar S]]

Current revision

Crystal Structure of C-terminal domain of nucleocapsid protein from SARS-CoV-2 in complex with ampicillin

PDB ID 8w6w

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