9gju
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of replicating Nipah Virus RNA Polymerase Complex - RNA-bound state== | |
| - | + | <StructureSection load='9gju' size='340' side='right'caption='[[9gju]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9gju]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Henipavirus_nipahense Henipavirus nipahense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GJU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gju OCA], [https://pdbe.org/9gju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gju RCSB], [https://www.ebi.ac.uk/pdbsum/9gju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gju ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Henipavirus nipahense]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ditter K]] | ||
| + | [[Category: Dybkov O]] | ||
| + | [[Category: Hillen HS]] | ||
| + | [[Category: Sala F]] | ||
| + | [[Category: Urlaub H]] | ||
Current revision
Structure of replicating Nipah Virus RNA Polymerase Complex - RNA-bound state
| |||||||||||
