9k9t

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m (Protected "9k9t" [edit=sysop:move=sysop])
Current revision (08:24, 5 March 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9k9t is ON HOLD
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==MPXV DNA polymerase in complex with CDV==
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<StructureSection load='9k9t' size='340' side='right'caption='[[9k9t]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
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Authors: Xie, Y.F., Kuai, L., Peng, Q., Wang, Q., Wang, H., Li, X.M., Qi, J.X., Ding, Q., Shi, Y., Gao, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9k9t]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9K9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9K9T FirstGlance]. <br>
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Description: MPXV DNA polymerase in complex with CDV
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.96&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9k9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9k9t OCA], [https://pdbe.org/9k9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9k9t RCSB], [https://www.ebi.ac.uk/pdbsum/9k9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9k9t ProSAT]</span></td></tr>
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[[Category: Qi, J.X]]
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</table>
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[[Category: Shi, Y]]
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== Function ==
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[[Category: Wang, H]]
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[https://www.uniprot.org/uniprot/DPOL_MONPV DPOL_MONPV] Catalyzes DNA synthesis. Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral OPG148 and OPG116 proteins, thereby forming the DNA polymerase holoenzyme. Displays 3'- to 5' exonuclease activity. Might participate in viral DNA recombination. Does not perform OPG116/D4synthesis across an abasic site.[UniProtKB:P06856]
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[[Category: Kuai, L]]
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__TOC__
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[[Category: Peng, Q]]
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</StructureSection>
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[[Category: Gao, F]]
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[[Category: Large Structures]]
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[[Category: Li, X.M]]
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[[Category: Monkeypox virus]]
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[[Category: Xie, Y.F]]
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[[Category: Ding Q]]
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[[Category: Wang, Q]]
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[[Category: Gao F]]
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[[Category: Ding, Q]]
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[[Category: Kuai L]]
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[[Category: Li XM]]
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[[Category: Peng Q]]
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[[Category: Qi JX]]
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[[Category: Shi Y]]
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[[Category: Wang H]]
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[[Category: Wang Q]]
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[[Category: Xie YF]]

Current revision

MPXV DNA polymerase in complex with CDV

PDB ID 9k9t

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OCA

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