8ze8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Arf-GTPase activating protein Asap1 SH3 domain in complex with 440 Kd Ankyrin-B fragment== | |
| - | + | <StructureSection load='8ze8' size='340' side='right'caption='[[8ze8]], [[Resolution|resolution]] 2.07Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ze8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZE8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ze8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ze8 OCA], [https://pdbe.org/8ze8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ze8 RCSB], [https://www.ebi.ac.uk/pdbsum/8ze8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ze8 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Li | + | [https://www.uniprot.org/uniprot/ASAP1_MOUSE ASAP1_MOUSE] May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis (By similarity). Posseses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Chen K]] | ||
| + | [[Category: He Y]] | ||
| + | [[Category: Li Y]] | ||
| + | [[Category: Zhang M]] | ||
| + | [[Category: Zhao Y]] | ||
Current revision
Arf-GTPase activating protein Asap1 SH3 domain in complex with 440 Kd Ankyrin-B fragment
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Categories: Homo sapiens | Large Structures | Mus musculus | Chen K | He Y | Li Y | Zhang M | Zhao Y
