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7c6p

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Current revision (10:45, 12 March 2025) (edit) (undo)
 
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<StructureSection load='7c6p' size='340' side='right'caption='[[7c6p]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='7c6p' size='340' side='right'caption='[[7c6p]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7c6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C6P FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C6P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SQH:2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one'>SQH</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SQH:2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one'>SQH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c6p OCA], [https://pdbe.org/7c6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c6p RCSB], [https://www.ebi.ac.uk/pdbsum/7c6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c6p ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c6p OCA], [https://pdbe.org/7c6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c6p RCSB], [https://www.ebi.ac.uk/pdbsum/7c6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c6p ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
 
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[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
 
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== Function ==
 
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[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Li J]]
[[Category: Li J]]

Current revision

Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid

PDB ID 7c6p

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