9l0d
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the human MON1A/CCZ1/C18orf8 complex== | |
| - | + | <StructureSection load='9l0d' size='340' side='right'caption='[[9l0d]], [[Resolution|resolution]] 3.41Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9l0d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L0D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.41Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l0d OCA], [https://pdbe.org/9l0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l0d RCSB], [https://www.ebi.ac.uk/pdbsum/9l0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l0d ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MON1A_HUMAN MON1A_HUMAN] Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).[UniProtKB:Q6PDG8]<ref>PMID:23084991</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Han Y]] | ||
| + | [[Category: Pan L]] | ||
| + | [[Category: Tang Y]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Cryo-EM structure of the human MON1A/CCZ1/C18orf8 complex
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Categories: Homo sapiens | Large Structures | Han Y | Pan L | Tang Y | Zhang Y
