User:Elizabeth Yowell/SandboxGiavanna

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Revision as of 19:22, 25 March 2025

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 <StructureSection load='7UHB' size='350' frame= 'true' side= 'right' caption='AHB2 Inhibitor 7UHB' scene ='10/1075216/Practice/1'>
 ==Introduction==
-Covid was a terrible pandemic that required a vaccine and here it is!
+==Introduction==
 SARS-CoV-2 better known as Covid-19 sent the world into a [https://www.who.int/europe/emergencies/situations/covid-19 global pandemic]. In order to create a vaccine, it was essential to understand how SARS-CoV-2 infected us.
-The enzyme angiotensin converting enzyme 2 (ACE2) is attached to our cell membranes bound to a receptor binding domain (RBD) <ref name="Borkotoky">DOI:10.1007/s11033-022-08193-4</ref>.
+The enzyme angiotensin converting enzyme 2 (ACE2) is attached to our cell membranes bound to a receptor binding domain (RBD) <ref name="Borkotoky">DOI:10.1007/s11033-022-08193-4</ref>. The spike protein of SARS-CoV-2 enters our bodies and binds to the RBD, allowing the spike protein access to ACE2 and our host cells <ref name=”Jackson”>DOI:10.1038/s41580-021-00418-x</ref>. Once the spike protein has access to our host cells, it is able to further infect our cells and spread the virus throughout our bodies, causing us to get sick. In order to create an effective vaccine, the pathway between the spike protein and the RBD needs to be [https://www.sciencedirect.com/science/article/pii/S0166354223000190 interrupted].
 <scene name='10/1075216/Practice/2'>Overview Image</scene>