8uo5

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Current revision (21:35, 26 March 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8uo5 is ON HOLD until Paper Publication
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==Protein Phosphatase 2A B55 subunit in complex with IER5==
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<StructureSection load='8uo5' size='340' side='right'caption='[[8uo5]], [[Resolution|resolution]] 3.27&Aring;' scene=''>
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Authors: Jones, D.T.D., Blacklow, S.C., Cao, R., Rawson, S.D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8uo5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UO5 FirstGlance]. <br>
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Description: Protein Phosphatase 2A B55 subunit in complex with IER5
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.27&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Cao, R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uo5 OCA], [https://pdbe.org/8uo5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uo5 RCSB], [https://www.ebi.ac.uk/pdbsum/8uo5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uo5 ProSAT]</span></td></tr>
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[[Category: Jones, D.T.D]]
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</table>
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[[Category: Rawson, S.D]]
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== Function ==
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[[Category: Blacklow, S.C]]
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[https://www.uniprot.org/uniprot/2AAA_HUMAN 2AAA_HUMAN] The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.<ref>PMID:16580887</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Blacklow SC]]
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[[Category: Cao R]]
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[[Category: Jones DTD]]
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[[Category: Rawson SD]]

Current revision

Protein Phosphatase 2A B55 subunit in complex with IER5

PDB ID 8uo5

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