3goa

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Current revision (22:36, 26 March 2025) (edit) (undo)
 
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<StructureSection load='3goa' size='340' side='right'caption='[[3goa]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3goa' size='340' side='right'caption='[[3goa]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3goa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GOA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3goa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GOA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetyl-CoA_C-acyltransferase Acetyl-CoA C-acyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.16 2.3.1.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3goa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3goa OCA], [https://pdbe.org/3goa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3goa RCSB], [https://www.ebi.ac.uk/pdbsum/3goa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3goa ProSAT], [https://www.topsan.org/Proteins/CSGID/3goa TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3goa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3goa OCA], [https://pdbe.org/3goa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3goa RCSB], [https://www.ebi.ac.uk/pdbsum/3goa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3goa ProSAT], [https://www.topsan.org/Proteins/CSGID/3goa TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FADA_SALTY FADA_SALTY]] Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity).
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[https://www.uniprot.org/uniprot/FADA_SALTY FADA_SALTY] Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/3goa_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/3goa_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetyl-CoA C-acyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, S M]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Anderson, W F]]
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[[Category: Anderson SM]]
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[[Category: Structural genomic]]
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[[Category: Anderson WF]]
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[[Category: Onopriyenko, O]]
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[[Category: Onopriyenko O]]
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[[Category: Papazisi, L]]
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[[Category: Papazisi L]]
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[[Category: Savchenko, A]]
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[[Category: Savchenko A]]
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[[Category: Skarina, T]]
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[[Category: Skarina T]]
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[[Category: Wawrzak, Z]]
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[[Category: Wawrzak Z]]
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[[Category: Acyltransferase]]
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[[Category: Csgid]]
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[[Category: Cytoplasm]]
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[[Category: Fatty acid]]
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[[Category: Fatty acid metabolism]]
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[[Category: Idp01071]]
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[[Category: Lipid degradation]]
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[[Category: Lipid metabolism]]
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[[Category: Metabolism]]
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[[Category: Phospholipid]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the Salmonella typhimurium FadA 3-ketoacyl-CoA thiolase

PDB ID 3goa

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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